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A systematic review was undertaken of published epidemiological studies describing the pattern of HSV-1 or HSV-2 by age, and the coincidence of the two viral infections. This was not evident in "high risk" populations or in the United States. This increased risk of HSV-2 in those with HSV-1 infection does not agree with the results of prospective studies where there is a non-significant trend towards a lower risk of HSV-2 infection associated with previous HSV-1 infection. This confounding could mask any protective effect of HSV-1, which is hinted at, but not demonstrated, in prospective and adjusted studies. National Center for Biotechnology Information , U. Journal List Sex Transm Infect v. Sex Transm Infect. K Looker and G Garnett.
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Posted by Jennifer Allen in Herpes Simplex 2. Herpes simplex 2 is one of the two viruses that cause herpes. Herpes simplex 2 virus causes genital herpes, also known as herpes type 2. The other virus is known as herpes simplex 1 and causes orofacial herpes, also known as sores. Both herpes viruses can cause sores but the herpes simplex 2 causes sores in the genital area, unlike the herpes simplex 1 virus that causes sores in the facial area, mouth and neck. Herpes simplex 2 causes a chronic viral infection. Practically, the virus is transmitted from one person to another upon sexual and even nonsexual but physical contact, thereby undergoing incubation and causing an outbreak followed by a subsiding of the symptoms only to cause a remission and then several outbreaks but with reducing severity. It may seem that the symptoms have completely subsided over a period of time and one may feel cured of herpes. But the virus continues to live on in the human body and can get triggered through incubation in the future. Hence, it is medically known as a chronic infection or condition.